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Glucose-6-Phosphate Dehydrogenase (G-6-PD) Hamburg, a New Variant with Chronic Nonspherocytic Haemolytic Anaemia

✍ Scribed by Dr. Manfred Gahr; Werner Schröter

Book ID
114725609
Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
488 KB
Volume
4
Category
Article
ISSN
0014-2972

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A new glucose-6-phosphate dehydrogenase
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✍ Gian Franco Gaetani; Silvana Galiano; Cecilia Melani; Maurizio Miglino; Gian Luc 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 405 KB

A new deficient variant of glucose-6-phosphate dehydrogenase (G6PD) causing severe congenital nonspherocytic hemolytic anemia (CNSHA) is described. The variant enzyme, characterized by slow electrophoretic mobility, extreme in vivo and in vitro lability, high Km for G6P and strongly acidic pH optimu