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Glucose-6-Phosphate Dehydrogenase Johannesburg: A New Variant with Reduced Activity in a Patient with Congenital Non-spherocytic Haemolytic Anaemia

✍ Scribed by Doris Balinsky; E. Gomperts; Eftihia Cayanis; T. Jenkins; Davey Bryer; I. Bersohn; J. Metz


Book ID
114707935
Publisher
John Wiley and Sons
Year
1973
Tongue
English
Weight
423 KB
Volume
25
Category
Article
ISSN
0007-1048

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More than 80 variants of glucose-6-phosphate dehydrogenase (G6PD) are associated with chronic nonspherocytic haemolytic anaemia (CNSHA); however, the molecular basis of this association is not fully understood. We have used the polymerase chain reaction and nucleotide sequence analysis to characteri