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Chromosome abnormalities and MLL rearrangements in acute myeloid leukemia of infants

✍ Scribed by Inaba, H; Katano, N; Horikoshi, Y; Eguchi, H; Miyake, M; Satake, N; Maseki, N; Nishiyama, M; Kobayashi, H; Sakurai, M

Book ID: 110054228
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 82 KB
Volume: 13
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2401439

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## Abstract Rearrangements of __MLL__ are regarded as primary oncogenic events in acute leukemia. We report the case of a patient with acute myeloid leukemia with a complex abnormal karyotype at diagnosis who showed a putative stem line with monosomy 5 and a rearrangement of chromosome 17 as the on