Chromosome abnormalities and fragile sites in human melanoma
β Scribed by Gabriella Sozzi; Monica Miozzo; Carla Calderone; Giuseppe Fossati; Marco A. Pierotti; Natale Cascinelli; Giuseppe Della Porta
- Book ID
- 119104717
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 404 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0165-4608
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In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions als
The fragile site at Xq27 which is associated with X-linked retardation with macroorchidism has been studied in 21 retarded males. These males were from 12 families, and studies of nine of the familes were possible. Detection of carrier females is difficult, especially with increasing age. The fragil
The chromosomal gaps associated with fragile sites at 2q11, 10q23, 11q13, 16q22, 20p11 and Xq27 do not stain with silver nitrate as do NOR regions of the acrocentric chromosomes.