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Fragile sites, chromosome evolution, and human neoplasia

✍ Scribed by Rosa Miró; Inmaculada Concepción Clemente; Carmen Fuster; José Egozcue

Publisher
Springer
Year
1987
Tongue
English
Weight
439 KB
Volume
75
Category
Article
ISSN
0340-6717

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✦ Synopsis

In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates.

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