A cohort study of 29 nurses who constantly handled cytostatic drugs, and 29 controls matched according to sex and age, was carried out between 1983 and 1986. Cytogenetic damage was assessed by sister chromatid exchanges (SCE) and chromosomal aberrations. No significant increase in mean number of SCE
Chromosome aberrations in lymphocytes of nurses handling cytostatic agents
β Scribed by Eeva Nikula, Kalevi Kiviniitty, Jaakko Leisti and Pentti J Taskinen
- Book ID
- 120573674
- Publisher
- Scaninavian Journal of Work, Environment, and Health
- Year
- 1984
- Tongue
- English
- Weight
- 532 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0355-3140
- DOI
- 10.2307/40965035
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Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals we
The effects of handling antineoplastic drugs were examined in 17 nurses working in a pneumology department in a hospital in the Paris area. Twenty-five others in the same department who were not handling such drugs acted as controls. Exposure to antineoplastic drugs was evaluated by questionnaire an