Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals we
Chromosomal aberrations in peripheral lymphocytes of nurses and physicians handling antineoplastic drugs
β Scribed by T. Grummt; H.-J. Grummt; G. Schott
- Book ID
- 113255812
- Publisher
- Elsevier Science
- Year
- 1993
- Weight
- 365 KB
- Volume
- 302
- Category
- Article
- ISSN
- 0165-7992
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## Abstract In this study we examined the structural chromosomal aberrations (CA) and sister chromatid exchanges (SCE) of 12 nurses handling moderate quantities of antineoplastic drugs. Urinary thioethers were also measured to assess the potential exposure to alkylβating drugs. Two control groups w
A cohort study of 29 nurses who constantly handled cytostatic drugs, and 29 controls matched according to sex and age, was carried out between 1983 and 1986. Cytogenetic damage was assessed by sister chromatid exchanges (SCE) and chromosomal aberrations. No significant increase in mean number of SCE
The effects of handling antineoplastic drugs were examined in 17 nurses working in a pneumology department in a hospital in the Paris area. Twenty-five others in the same department who were not handling such drugs acted as controls. Exposure to antineoplastic drugs was evaluated by questionnaire an