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Chromosome aberrations in 60 primary ovarian carcinomas

✍ Scribed by I. Pejovic; S. Heim; N. Mandahl; F. Mitelman


Book ID
119105673
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
85 KB
Volume
63
Category
Article
ISSN
0165-4608

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Cytogenetic analysis was performed on short-term cultures of primary ovarian carcinomas from 62 patients. Cytogenetic analysis was successful in 59 cases. Clonal chromosome aberrations were detected in 35 tumors. Only numerical changes or a single structural change were found in five carcinomas: tri

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## Abstract Twenty malignant effusions secondary to ovarian cancer have been cytogenetically analyzed directly and after short __in vitro__ culture. With the exception of one sample characterized by trisomy 3, all cases displayed clonal structural rearrangements. Chromosomes 1 and 3 were most frequ