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Chromosome 3 and the isolation of a tumor suppressor gene

✍ Scribed by Susan L. Naylor; Maria C. Daly; Rui Hua Xiang; Charles H. Hensel; Klaas Kok; Helene Carlson; Ann M. Killary; Harry Drabkin; Charles Buys

Book ID
113253806
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
161 KB
Volume
84
Category
Article
ISSN
0165-4608

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## Abstract Loss of heterozygosity (LOH) on chromosome 3p is a common event in cervical cancer and typically occurs in a dispersed pattern involving several loci. This implies that more than one resident tumor‐suppressor gene is involved in the genesis of these tumors; however, specific targets rem