Chromosomal variation in lymphoblastoid cell lines
β Scribed by Matthew D. Shirley; Joseph D. Baugher; Eric L. Stevens; Zhenya Tang; Norman Gerry; Christine M. Beiswanger; Dorit S. Berlin; Jonathan Pevsner
- Book ID
- 112099725
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 714 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1059-7794
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Transformation of peripheral B lymphocytes by EpsteinβBarr virus (EBV) is the method of choice for generating lymphoblastoid cell lines (LCLs). This method has been in use for the last two decades with a high success rate. With a somatic mutation rate of 0.3% and ease of cell maintenanc
Three Epstein-Barr-virus-transformed lymphoblastoid cell lines (LCL) were analysed on the basis of their CD23 expression. Levels of EBV-DNA were compared in the positive and negative subpopulations. Two lines were further analysed with regard to EBNA, cytoplasmic immunoglobulin (clg) and lytic (EA/V