Variation in arsenic-induced sister chromatid exchange in human lymphocytes and lymphoblastoid cell lines
β Scribed by Ronald E. Rasmussen; Daniel B. Menzel
- Book ID
- 117768224
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 717 KB
- Volume
- 386
- Category
- Article
- ISSN
- 1383-5742
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual baseline SCE frequencies. This investigation identifies and quantifies the major sources of preparative and biological variation ass
The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. The addition of inorganic trivalent arsenic (Na2HAsO4) 10-6M and 2 x 10-6M induces a significant and dose-dependent increase of SCE. This phenomenon is as sensitiv