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Chromosomal studies of leukemic and preleukemic Fanconi's anemia patients

✍ Scribed by Roland Berger; Alain Bernheim; Maryvonne Coniat; Danièle Vecchione; Gérard Schaison


Publisher
Springer
Year
1980
Tongue
English
Weight
720 KB
Volume
56
Category
Article
ISSN
0340-6717

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Effects of alkylating agents on lymphocy
✍ Božena Novotná; Petr Goetz; Naděžda I. Surkova 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 418 KB

The frequency of sister chromatid exchanges (SCE) and chromosome aberrations and the dynamics of cell division in peripheral blood lymphocytes of four patients with Fanconi's anemia were studied after in vitro exposure to alkylating agents TEPA and mitomycin. SCE frequency was significantly increase