A model of the sister chromatid exchange (SCE) process is outlined as a replication mechanism to bypass DNA crosslinks. The model suggests that when normal bidirectional replication advances from both sides towards a crosslink along the two opposite parental strands, the complementary parental stran
โฆ LIBER โฆ
Bloom's syndrome and Fanconi's anemia: Demonstration of two distinctive patterns of chromosome disruption and rearrangement
โ Scribed by Schroeder, Traute M. ;German, James
- Publisher
- Springer-Verlag
- Year
- 1974
- Weight
- 792 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0018-7348
No coin nor oath required. For personal study only.
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Bloom's syndrome (BS) and EM9 cells both display elevated frequencies of sister chromatid exchange (SCE) following growth for two rounds of DNA replication in bromodeoxyuridine (BrdU)-containing medium. To learn whether hyperresponsiveness to BrdU itself might play a role in causing the SCE elevatio