Chromosomal Insertion and Amplification of Human Papillomavirus 16 DNA Sequences in a Cell Line of Argyrophil Small Cell Carcinoma of the Uterine Cervix
โ Scribed by Hori, Tada-aki ;Ichimura, Hiroshi ;Minamihisamatsu, Masako ;Takahashi, Ei-ichi ;Yamauchi, Masatake ;Hama, Yuko ;Kurimura, Osamu ;Yamasaki, Masato ;Kurimura, Takashi
- Book ID
- 108579298
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1991
- Tongue
- English
- Weight
- 561 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0910-5050
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A new cell line, designated TC-YIK, was established from YIK-1 tumor cells, derived from argyrophil small cell carcinoma (ASCC) of the uterine cervix, and serially heterotransplanted into nude mice, integrating human papillomavirus type 16 (HPV16) DNA. The population doubling time of TC-YIK was appr
A total of six cervical carcinoma cell lines, of which two contained human papillomavirus (HPV) type 16 and four contained HPV type 18 DNA, were examined for viral RNA expression by spot-blot hybridization. All six cell lines contained HPV-specific cytoplasmic poly(A)-containing RNA. The same RNA sp
The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or as representing the views of the Department of the Army of the Department of Defense.