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Chromatin modifications and DNA double-strand breaks: the current state of play

✍ Scribed by Karagiannis, T C; El-Osta, A


Book ID
110056994
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
131 KB
Volume
21
Category
Article
ISSN
0887-6924

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## Abstract DNA double‐strand breaks (DSBs) are the most hazardous lesions arising in the genome of eukaryotic organisms, and yet occur normally during DNA replication, meiosis, and immune system development. The efficient repair of DSBs is crucial in maintaining genomic integrity, cellular viabili