Cholinesterase inhibition by vecuronium and pancuronium in human airways
β Scribed by X. Norel; C. Labat; D. De Santis; I. Gorenne; E. Dulmet; F. Rossi; C. Brink
- Book ID
- 118346513
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 344 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0024-3205
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The effect of galanthamine (GAL) and its 2 major metabolites on human cholinesterases has been explored. Epigalanthamine, a diastereomer of GAL, was 130-times less potent in vitro in its effect on acetylcholinesterase (AChE) in erythrocytes than the parent compound, and it did not differ significant
## Abstract Methamidophos (O, Sβdimethyl phosphoramidothioate) inhibition of human erythrocyte and plasma cholinesterase was studied __in vitro.__ The pseudoβbiomolecular rate constant of inhibition was 3.14 Β± 0.22 Γ 10^3^ M^β1^ min^β1^ for erythrocyte cholinesterase and 1.85 Β± 0.01 Γ 10^3^ M^β1^ m