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Cholecystokinin receptor antagonist, loxiglumide, inhibits invasiveness of human pancreatic cancer cell lines

โœ Scribed by Manabu Hirata; Masaki Itoh; Akira Tsuchida; Hideo Ooishi; Keiji Hanada; Goro Kajiyama


Book ID
115932211
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
366 KB
Volume
383
Category
Article
ISSN
0014-5793

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Inhibitory effects of a cholecystokinin
โœ Hideki Morimoto; Dr. Yoshinori Nio; Michihiko Tsubono; Chen-Chiu Tseng; Kazuya K ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 676 KB

The effects of cholecystokinin (CCK) and a CCK antagonist, loxiglumide (CR-1505), on four freshly separated and six xenografted human pancreatic cancers, were investigated. The level of DNA synthesis in only one of five tested pancreatic cancers was enhanced by CCK at concentrations of 0.01-10 nM, w