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Cholecystokinin regulates the invasiveness of human pancreatic cancer cell lines via protein kinase C pathway

✍ Scribed by Hirata, Manabu; Tsuchida, Akira; Iwao, Toshiyasu; Eguchi, Noriaki; Sasaki, Tamito; Matsubara, Kenji; Yamamoto, Shigeru; Morinaka, Kenji; Kawasaki, Yohsuke; Kajiyama, Goro

Book ID: 122449644
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 167 KB
Volume: 114
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(98)81897-0

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## Abstract Overexpression of cyclooxygenase‐2 (COX‐2) and elevation of its derivative prostaglandin E~2~ (PGE~2~) are implicated in human esophageal squamous cell carcinoma. The expression of c‐Myc, an oncogenic transcription factor, is also upregulated in this malignant disease. This study sought