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Loxiglumide (CR1505), a cholecystokinin antagonist, specifically inhibits the growth of human pancreatic cancer lines xenografted into nude mice

โœ Scribed by Yoshinori Nio; Michihiko Tsubono; Hideki Morimoto; Kazuya Kawabata; Yoshikazu Masai; Hitoshi Hayashi; Tadao Manabe; Masayuki Imamura; Manabu Fukumoto


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
718 KB
Volume
72
Category
Article
ISSN
0008-543X

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๐Ÿ“œ SIMILAR VOLUMES


Inhibitory effects of a cholecystokinin
โœ Hideki Morimoto; Dr. Yoshinori Nio; Michihiko Tsubono; Chen-Chiu Tseng; Kazuya K ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 676 KB

The effects of cholecystokinin (CCK) and a CCK antagonist, loxiglumide (CR-1505), on four freshly separated and six xenografted human pancreatic cancers, were investigated. The level of DNA synthesis in only one of five tested pancreatic cancers was enhanced by CCK at concentrations of 0.01-10 nM, w