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CHK2 gene mutation underlies some familial breast cancers

✍ Scribed by Jane Bradbury


Book ID
117782597
Publisher
The Lancet
Year
2002
Tongue
English
Weight
60 KB
Volume
3
Category
Article
ISSN
1470-2045

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Family history is a well-recognized risk factor for the development of breast cancer. The isolation of BRCA1 and BRCA2 genes, the two major predisposing genes in familial and to early onset breast and ovarian cancer, has resulted to the identification of a large number of families with mutations in