Mutation analysis in the BRCA2 gene in primary breast cancers
β Scribed by Miki, Yoshio; Katagiri, Toyomasa; Kasumi, Fujio; Yoshimoto, Takamasa; Nakamura, Yusuke
- Book ID
- 109916289
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 397 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1061-4036
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In this study we genotyped Turkish breast/ovarian cancer patients for BRCA1/BRCA2 mutations: protein truncation test (PTT) for exon 11 BRCA1 of and, multiplex PCR and denaturing gradient gel electrophoresis (DGGE) for BRCA2, complemented by DNA sequencing. In addition, a modified restriction assay w