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Chirality transfer in the aza-[2,3]-Wittig sigmatropic rearrangement

โœ Scribed by Anderson, James C.; Ford, J. Gair; Whiting, Matthew


Book ID
119961226
Publisher
Royal Society of Chemistry
Year
2005
Tongue
English
Weight
394 KB
Volume
3
Category
Article
ISSN
1477-0520

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The aza-[2,3]-Wittig sigmatropic rearran
โœ James C Anderson; Philippe Dupau; D Craig Siddons; Stephen C Smith; Martin E Swa ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 134 KB

The aza-[2,3]-Wittig sigmatropic rearrangement of Z(C)-alkenes can be achieved through the use of a trimethylsilyl anion stabilising group. The major diastereoisomer complements previous results and allows access to each diastereoisomer of the homoallylic amine products. A transition state model is