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Chirality and Spectroscopic Changes Induced by the Recognition of Ethyl 5-Amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl Carbamate Analogs by Tubulin

✍ Scribed by V. Peyrot; P. Barbier; M. Sarrazin; C. Briand; J. M. Andreu


Book ID
111412682
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
877 KB
Volume
70
Category
Article
ISSN
0031-8655

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Synthesis of [14C]CI-980, ethyl [5-amino
✍ Peter W. K. Woo; Helen T. Lee πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 French βš– 408 KB

## Abstract [^14^C]CI‐980 (14b) was synthesized in eight steps starting from [U‐^14^C]benzene (5), which was converted to bromo[^14^C]benzene (6) in the presence of tetrabutylammonium bromide as catalyst. Reaction of 6 with the anion of __N__‐ethoxycarbonyl‐__N__′‐methoxy‐__N__′‐methyl‐L‐alaninamid