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Chiral synthons for the elaboration of mevinic acid analogues

โœ Scribed by Frank Bennett; David W. Knight; Garry Fenton


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
248 KB
Volume
29
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Mevinic acids and analogues: preparation
โœ Yuh-Lin Yang; J.R. Flack ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 213 KB

The preparation of methyl 3-O-tert-butyldiphenylsilyl-2,4-dideoxy-B-D-erythrohexopyranoside, a key chiral intermediate for mevinic acids, and its elaboration into four mevinate analogues are described.

A new strategy for the synthesis of mevi
โœ Pascal Boquel; Yves Chapleur ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 170 KB

The reaction of the allylic carbonate 2 with organocopper derivatives is the key step of a new strategy for the synthesis of mevinic acid analogues.

Triflates as synthons for the synthesis
โœ Ingo Weber; Pierre Potier; Josiane Thierry ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 207 KB

A simple synthesis of various 6-amino-2-substitutcd hexanoic acids has been developed starting from lysine via the triflate of 6-amino-2-hydroxy hexanoic acid. The same reactions have also been successfully applied starting from the lysyl-proline sequence. The lysine analogues have been introduced i