Chiral separations of β-blocking drug substances using chiral stationary phases
✍ Scribed by Jens Ekelund; Anja van Arkens; Kirsten Brønnum-Hansen; Karen Fich; Lars Olsen; Poul Vibholm Petersen
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 592 KB
- Volume
- 708
- Category
- Article
- ISSN
- 1873-3778
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📜 SIMILAR VOLUMES
Many active drugs are racemic mixtures. Because the two enantiomers of a racemate often cause different pharmacological responses, the use of optically pure isomers is desirable and may be soon required. Cyclodextrin-bonded silica gel can be used as chiral stationary phase (CSP) in liquid chromatogr
## Abstract Chloroacyl pentyl β‐cyclodextrin derivatives were synthesized for use as gas chromatographic stationary phases. Capillary columns of identical phase ratios were prepared with the liquid undiluted monochloro‐, dichloro‐, and trichloroactyl phases and the respective column efficiency, cap