Chiral selection in template-directed RNA synthesis and the case for a prochiral ancestor of RNA
โ Scribed by Gerald F. Joyce; Leslie E. Orgel; Stanley L. Miller
- Publisher
- Springer Netherlands
- Year
- 1986
- Tongue
- English
- Weight
- 40 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1573-0875
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Transcription factor one (TF1), a protein synthesized after infection of B. subtilis by phage SPO1, is a specific inhibitor of SPO1 in vitro transcription. In this paper, we investigate the effect of TF1 on SPO1-specific in vitro protein synthesis, using SPO1 DNA or messenger RNA as templates. Prote
## Abstract Nucleic acid synthesis is precisely controlled in living organisms by highly evolved protein enzymes. The remarkable fidelity of information transfer realized between template and product strands is the result of both the spatial selectivity of the polymerase active site for __WatsonโCr