Chiral reagents for the determination of enantiomeric excess and absolute configuration using NMR spectroscopy
β Scribed by Thomas J. Wenzel; James D. Wilcox
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 257 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0899-0042
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π SIMILAR VOLUMES
The LIS values produced by Eu(fodJ3 for the CF3-19F NMR signals of the MlTA e s t e r s of different stereoisomeric secondary alcohols have been measured. The applicability o f these values for assigning the absolute configuration of the alcohols has been studied. The advantages of t h i s method ov
## Abstract The enantiomeric purities of disubstituted Ξ²βlactams were determined by ^1^H and ^13^C NMR spectroscopy using tris[3β(trifluoromethylhydroxymethylene)βdβcamphorato]europium(III), Eu(tfc)~3~, as a chiral shift reagent. Using a [Eu(tfc)~3~]/[lactam] ratio of 0.5, most of the resonances we