A novel s y n t h e t i c approach has been developed f o r t h e s y n t h e s i s of i n o r g a n i c pyrophosphate which a l l o w s t h e i s o t o p e s 170 and " 0 t o be i n c o r p o r a t e d a t P' t o g i v e c h i r a l l y l a b e l l e d material.
Chiral inorganic [16O, 17O, 18O]thiophosphate: Synthesis and stereochemical analysis
✍ Scribed by John R.P. Arnold; Richard C. Bethell; Gordon Lowe
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 849 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0045-2068
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📜 SIMILAR VOLUMES
The preparation of 1 7 0 -and 180-labelled hypophosphate by oxidation of diphosphite (P2-P4 acid) with iodine-water is described. The 162 MHz NMR 31P(18O) isotope shift of 1 8 0 -l a b e l l e d hypophosphate is 2.42 Hz (0.0149 ppm), the relatively large value compared to l\*O-pyrophosphate, 1.73 Hz
## Abstract 3‐Chloroperbenzoic acid‐^17^O,^18^O was prepared from 3‐chlorobenzoyl chloride and hydrogen peroxide‐^17^O,^18^O (obtained by subjecting water‐^17^O,^18^O. Nitrobenzene‐^15^N was reduced to aniline‐^15^N, which was oxidised by 3‐chloroperbenzoic acid to nitrosobenzene‐^15^N. ^15^N and ^