✍ Scribed by Mei, Liang-yong; Yuan, Zhi-liang; Shi, Min
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
New chiral phosphinooxazolidines were prepared and examined as chiral ligands in Pd-catalyzed asymmetric allylic substitution reaction of 1,3-diphenyl-2propenyl acetate with dimethyl malonate or benzylamine. Enantioselectivity up to 9896 was observed.
Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate (8a) with a dimethyl malonate-BSA-LiOAc system has been successfully carried out in the presence of novel chiral phosphine-oxazinane ligands such as 5b in good yields with good enantioselectivities (up to 95% ee).
New chiral ligands, phosphinooxathianes 3 and 6, were synthesized easily and their ability as ligands were examined in Pd-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate to give an allylation product. Enantiomeric excess of up to 94% has been obtaine