Chiral doping of nematic phases and its application to the determination of absolute configuration

✍ Scribed by Silvia Pieraccini; Alberta Ferrarini; Gian Piero Spada

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 830 KB
• Volume: 20
• Category: Article
• ISSN: 0899-0042
• DOI: 10.1002/chir.20482

✦ Synopsis

Abstract

Doping nematic liquid crystals with nonracemic chiral compounds induces a twisted nematic (cholesteric) phase. The ability of solutes to twist the nematic phase may be related to the overall shape of the chiral dopant and consequently to its absolute configuration. The cholesteric induction is therefore a powerful tool complementary to chiroptical techniques to obtain stereochemical information on chiral molecules. Chirality, 2008. © 2007 Wiley‐Liss, Inc.