## Chiral capillary electrophoretic determination of the enantiomeric purity of tetrahydronaphthalenic derivatives, melatoninergic ligands, using highly sulfated â-cyclodextrins Using cyclodextrin capillary zone electrophoresis (CD-CZE), baseline separation of synthetic tetrahydronaphthalenic deri
Chiral capillary electrophoretic resolution of baclofen, gabaergic ligand, using highly sulfated cyclodextrins
✍ Scribed by Marie-Pierre Vaccher; Emmanuelle Lipka; Jean-Paul Bonte; Claude Vaccher
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 156 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0173-0835
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📜 SIMILAR VOLUMES
## Abstract The chiral resolution of baclofen was achieved by capillary electrophoresis using a fused‐silica capillary (60 cm×75 μm ID). The background electrolyte (BGE) was phosphate buffer (pH 7.0, 50 mM)‐acetonitrile (95:5 v/v) containing 10 mM β‐cyclodextrin. The applied voltage was 15 kV. The
## Abstract EKC methods for the enantiomeric resolutions of melatoninergic ligands were developed using anionic CDs (highly S‐α‐CD, highly S‐β‐CD, and highly S‐γ‐CD) as chiral selectors at acidic pH 2.5. The optimization of the various operational parameters (nature and concentration of the CD, pho