Optically Active 5-(Hydroxyalkyl)- and 5
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Bohrisch, Jörg ;Faltz, Heike ;Pätzel, Michael ;Liebscher, Jürgen
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Article
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1996
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John Wiley and Sons
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English
⚖ 513 KB
## Abstract α,β‐Unsaturated lactones or lactams 1 react with hydrazines 2 via Michael‐like addition and subsequent ring transformation by nucleophilic attack of the hitherto unchanged hydrazine nitrogen atom at the carbonyl carbon atom. The addition is highly trans‐stereoselective, thus affording o