ChemInform Abstract: Optically Active 5-(Hydroxyalkyl)- and 5-(Aminoalkyl)pyrazolidin-3- ones by Ring-Chain Transformation of α,β-Unsaturated Lactones or Lactams with Hydrazines.

ChemInform Abstract: Synthesis of Chiral

ChemInform Abstract: Synthesis of Chiral 4-(ω-Hydroxyalkyl)pyrazolidin-3-ones by Ring-Chain Transformation of α-Alkylidenelactones with Hydrazines.

✍ A. OTTO; B. ZIEMER; J. LIEBSCHER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Synthesis of Chiral 4-(ω-Hydroxyalkyl)pyrazolidin-3-ones by Ring-Chain Transformation of α-Alkylidenelactones with Hydrazines. -This is the first access to optically active 4-(ω-hydroxyalkyl)pyrazolidin-3-ones. The lactone (IX), however, cannot be transformed into the corresponding pyrazolidinone.