## Abstract Urokinaseβtype plasminogen activator (uPA) binds to its receptor, uPAR, on the surface of cancer cells, leading to the formation of plasmin. Rhabdomyosarcoma (RMS) cell lines secrete high levels of insulinβlike growth factor II (IGFβII), suggesting autocrine IGFs play a major role in th
Chemotactic effect of urokinase-type plasminogen activator on mouse spermatozoa in vitro
β Scribed by Ding, Xiaofang ;Li, Honggang ;Xiong, Chengliang
- Book ID
- 107472224
- Publisher
- Higher Education Press and Springer
- Year
- 2008
- Tongue
- English
- Weight
- 131 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1673-7342
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## Abstract The urokinaseβtype plasminogen activator receptor (uPAR, CD87) plays a central role in the plasminogen activation cascade, which participates in extracellular matrix degradation, cell migration and invasion. Here we performed a comprehensive immmunohistochemical evaluation of uPAR expre