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Modulation of urokinase-type plasminogen activator and metalloproteinase activities in cultured mouse mammary-carcinoma cells: Enhancement by paclitaxel and inhibition by nocodazole

✍ Scribed by Daniel F. Alonso; Hernán G. Farina; Carlos Arregui; Miguel A. Aon; Daniel E. Gomez

Publisher: John Wiley and Sons
Year: 1999
Tongue: French
Weight: 146 KB
Volume: 83
Category: Article
ISSN: 0020-7136
DOI: 10.1002/(sici)1097-0215(19991008)83:2<242::aid-ijc16>3.0.co;2-8

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Current evidence has suggested the possible involvement of ROS as signaling messengers in IL-1␤-or LPS-induced gene expression. We previously reported that both IL-1␤ and LPS induce uPA in RC-K8 human lymphoma cells. Here, we provide evidence that ROS-generating anthracycline antibiotics, including