A prospective study on the prognostic significance of urokinase-type plasminogen activator levels in breast cancer tissue
β Scribed by E. Shiba; Seung Jin Kim; Tetsuya Taguchi; Masaaki Izukura; Tetsuro Kobayashi; Junkoh Furukawa; Eiji Yayoi; Eisei Shin; Yuichi Takatsuka; Hiroki Koyama; Shin-ichiro Takai
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 154 KB
- Volume
- 123
- Category
- Article
- ISSN
- 1432-1335
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## Urokinase -type plasminogen activator (u-PA) is thought to be implicated in cancer invasion and metastasis. The aim of this study was to determine whether the u-PA content of cancer tissue is a prognostic factor in bladder cancer. Tissue samples from 46 patients with bladder cancer were assesse
Background. Cathepsin D is a lysosomal protease overexpressed and abnormally secreted in most breast cancer cells. Several retrospective clinical studies have shown that cathepsin D is an independent prognostic factor in breast cancer that is associated with a higher risk of recurrence and a shorter