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A prospective study on the prognostic significance of urokinase-type plasminogen activator levels in breast cancer tissue

✍ Scribed by E. Shiba; Seung Jin Kim; Tetsuya Taguchi; Masaaki Izukura; Tetsuro Kobayashi; Junkoh Furukawa; Eiji Yayoi; Eisei Shin; Yuichi Takatsuka; Hiroki Koyama; Shin-ichiro Takai


Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
154 KB
Volume
123
Category
Article
ISSN
1432-1335

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Background. Cathepsin D is a lysosomal protease overexpressed and abnormally secreted in most breast cancer cells. Several retrospective clinical studies have shown that cathepsin D is an independent prognostic factor in breast cancer that is associated with a higher risk of recurrence and a shorter