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Chemopreventive activity of chlorophyllin against mouse skin carcinogenesis by benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide

✍ Scribed by Kwang-Kyun Park; Young-Joon Surh


Book ID
116123478
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
629 KB
Volume
102
Category
Article
ISSN
0304-3835

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Chlorophyllin (CHL), a water soluble derivative of the green pigment chlorophyll, was evaluated for its antimutagenic activity towards benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE). CHL suppressed dose-dependently the formation of 8-azaguanine-resistant mutant colonies in Salmonella typhimurium