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Chemoenzymatic Preparation of Optically Active β-Aminocyclohexanols and Their Application in the Enantioselective Addition of Diethylzinc to Benzaldehyde.

✍ Scribed by Javier Gonzalez-Sabin; Vicente Gotor; Francisca Rebolledo


Publisher
John Wiley and Sons
Year
2004
Weight
109 KB
Volume
35
Category
Article
ISSN
0931-7597

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✍ G. CHELUCCI; D. BERTA; D. FABBRI; G. A. PINNA; A. SABA; F. ULGHERI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Enantioselective Addition of Diethylzinc to Benzaldehyde in the Presence of Sulfur-Containing Pyridine Ligands. -In some cases ligands, which differ only in the C-8 carbon configuration, cf. methods B) and E), give the opposite configuration of phenylpropanol (III). Surprisingly, method C) leads to