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Chemoenzymatic enantioselective synthesis of 3-hydroxy-2-pyrrolidinones and 3-hydroxy-2-piperidinones

✍ Scribed by Ahmed Kamal; K.Venkata Ramana; A.Venkata Ramana; A.Hari Babu


Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
226 KB
Volume
14
Category
Article
ISSN
0957-4166

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✍ Monika Raj; Nagarathanam Veerasamy; Vinod K. Singh πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 French βš– 359 KB

Highly enantioselective catalytic synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles was achieved by using primary-tertiary diamine-BrΓΈnsted acid catalyst in both organic medium and aqueous medium. The products, thus obtained act as potential anticonvulsants.