Highly enantioselective synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles, potential anticonvulsants

✍ Scribed by Monika Raj; Nagarathanam Veerasamy; Vinod K. Singh

• Publisher: Elsevier Science
• Year: 2010
• Tongue: French
• Weight: 359 KB
• Volume: 51
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2010.02.082

✦ Synopsis

Highly enantioselective catalytic synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles was achieved by using primary-tertiary diamine-Brønsted acid catalyst in both organic medium and aqueous medium. The products, thus obtained act as potential anticonvulsants.