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Enantioselective synthesis of both enantiomers of 3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone

✍ Scribed by Pelayo Camps; Francesc Pérez; Núria Soldevilla


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
268 KB
Volume
40
Category
Article
ISSN
0040-4039

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Chemoenzymatic synthesis of both enantio
✍ Ayhan S. Demir; Asuman Aybey; Özge Sesenoglu; Fatos Polat 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 135 KB

4-Oxo-3,4-dihydro-2-chromen-3-yl acetate is synthesized using manganese(III)acetate starting from 2,3-dihydro-4Hchromen-4-one. K 2 CO 3 mediated hydrolysis of 4-oxo-3,4-dihdro-2-chromen-3-yl acetate furnished 3-hydroxy-2,3-dihydro-4Hchromen-4-one in high yield.The enantioselective hydrolysis of (±)-