𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Chemo-enzymatic synthesis of (−)-carba-2′,3′-dideoxythymidine and (−)-carba-2′,3′-dideoxy-3′-fluorothymidine

✍ Scribed by H. Baumgartner; M. Bodenteich; H. Griengl

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
120 KB
Volume
29
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 2′-Azido-2′,3′-didehydro-2′
Synthesis of 2′-Azido-2′,3′-didehydro-2′,3′-dideoxythymidine
✍ Mikhailopulo, Igor A. ;Zaitseva, Galina V. ;Vaaks, Elena V. ;Balzarini, Jan ;De 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 598 KB

## Abstract Compound 15 – the 2′‐azido analog of the anti‐HIV compound 2′,3′‐didehydro‐2′,3′‐dideoxythymidine – was synthesized. Treatment of 5′‐__O__‐trityl‐β‐D‐ribofuranosylthymine (1) with DAST or MSTF gave the 2,2′‐anhydro derivative 2. The latter and its 3′‐__O__‐benzoate 3 were used for the s

Synthesis and anti-HIV activities of pho
Synthesis and anti-HIV activities of phosphate triester derivatives of 3′-fluoro-2′,3′-dideoxythymidine and 3′-azido-2′,3′-dideoxythymidine
✍ Hitesh K. Agarwal; Gustavo F. Doncel; Keykavous Parang 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 169 KB

Fatty acyl-glycol phosphate triester conjugates of 3 0 -fluoro-2 0 ,3 0 -dideoxythymidine (FLT) were prepared in three steps from the reaction of diisopropylphoramidous dichloride with fatty acyl-substituted glycols, followed by a coupling reaction with FLT and oxidation with tert-butyl hydroperoxid

ChemInform Abstract: Synthesis of 2′,3′-
ChemInform Abstract: Synthesis of 2′,3′-Dideoxy-3′,3′-difluoro and 2′,3′-Dideoxy-2′,2′-difluoropyranosyl Nucleoside Analogues of Gemcitabine.
✍ Raul Fernandez; Sergio Castillon 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis and antiviral evaluation of en
Synthesis and antiviral evaluation of enantiomeric 2′,3′-dideoxy- and 2′,3′-didehydro-2′,3′-dideoxy-4′-thionucleosides
✍ Robert J. Young; Sue Shaw-Ponter; Jamie B. Thomson; J.Allen Miller; John G. Cumm 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 325 KB

The synthesis and antiviral evaluation of 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy 4'thionucleosides in both enantiomeric series are described. Enantiomeric 4-O-silylated-4hydroxymethyl-4-thiobutyrolactones, produced in high yield from chiral glycidols, provided suitable chiral synthons: phen

Stereoselective synthesis of 2′,3′-dideo
Stereoselective synthesis of 2′,3′-dideoxy-nucleosides via intramolecular glycosylation of phenyl 1-seleno-glycosides. Synthesis of 2′,3′-dideoxythymidine
✍ Jordi Lluís; MaIsabel Matheu; Sergio Castillón 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 230 KB

4-methoxy and 4-(2-trimethylsilylethoxy)pyrimidine bases were attached to the 5position of the phenyl 2,3-dideoxy-l-seleno-glycero-pentofuranoside moiety. The presence of the silyl protecting group in the base is necessary to lead to neutral 13-anhydro nucleosides by inlramolecular glycosylafion. Th