1-(2-O-Acetyl-3,5,6-tri-O-benzoyl-beta-D-glucofuranosyl)thymine (1) was converted into the 2,2'-anhydro derivative 4 by selective deacetylation, mesylation, and treatment with 1,8-diazabicyclo[5.4.0]undec-7-ene. Cleavage of the 2,2'-anhydro ring in 4 with hydrogen bromide or hydrogen chloride led to
Chemo-enzymatic synthesis of 2′,3′-dideoxy-3′-fluoro-β-d-guanosine via 2,3-dideoxy-3-fluoro-α-d-ribose 1-phosphate
✍ Scribed by Hironori Komatsu; Tadashi Araki
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 109 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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