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ChemInform Abstract: α-Oxymethyl Ketone Enolates for the Asymmetric Mannich Reaction. From Acetylene and N-Alkoxycarbonylimines to β-Amino Acids.

✍ Scribed by Claudio Palomo; Mikel Oiarbide; M. Concepcion Gonzalez-Rego; Arun K. Sharma; Jesus M. Garcia; Alberto Gonzalez; Cristina Landa; Anthony Linden


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
31
Category
Article
ISSN
0931-7597

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The reactions of enolizable carbonyl compounds with azomethine functions, usually referred to as Mannich-type reactions (also termed aza ± aldol reactions), result in the formation of b-amino acids, ketones, or aldehydes. [1] These reactions are conceptually equivalent to the aldol reactions, but, i

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