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ChemInform Abstract: Versatile Synthesis of Enantiomerically Pure trans-2,5-Disubstituted Pyrrolidines.

✍ Scribed by M. DOCKNER; N. A. SASAKI; P. POTIER


Book ID
112031783
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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Pyrrolidines 1 and 2 are obtained from D-Mannitol, giving good total yields and in an enantiomerically pure form. Some commentS and studies regarding pyrrolidine ring closure (key step) are also qorted. Over the last few years, interest in pyrrolidine-type derivatives has grown considerably, from b