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ChemInform Abstract: trans N-Methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)cycloprop-2-ene-1- carboxamides: Novel Lipophilic Kappa Opioid Agonists.

✍ Scribed by V. SABIN; D. C. HORWELL; A. T. MCKNIGHT; P. BROQUA


Book ID
101846693
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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trans N-Methyl-N-[2-(1-pyrrolidinyl)cycl
✍ V. Sabin; D.C. Horwell; A.T. McKnight; P. Broqua πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 236 KB

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Synthesis of high specific activity trit
✍ Brian R. De Costa; Andew Thurkauf; Richard R. Rothman; Arthur E. Jacobson; Kenne πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 French βš– 383 KB

## Abstract Optically pure tritium labeled 1__S__,2__S__‐(‐)‐__trans__‐2‐isothiocyanato‐N‐methyl‐N‐[2‐(1‐pyrrolidinyl)cyclohexyl]benzeneacetamide, an affinity ligand specific for the kappa opioid receptor was synthesized from optically pure 1__S__,2__S__‐(‐)‐__trans__‐2‐amino‐N‐methyl‐N‐[2‐(1‐pyrro