The synthesis and kappa opioid agonist activities of some lipophilic analogues of the kappa opioid agonist U-50488 incorporating motifs bearing two aromatic rings in place of the 3,4dichlorophenyl group are described. 1-carboxamide, 13, is a highly lipophilic chemically novel potent selective kappa
β¦ LIBER β¦
ChemInform Abstract: trans N-Methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)cycloprop-2-ene-1- carboxamides: Novel Lipophilic Kappa Opioid Agonists.
β Scribed by V. SABIN; D. C. HORWELL; A. T. MCKNIGHT; P. BROQUA
- Book ID
- 101846693
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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