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ChemInform Abstract: Total Synthesis of Polycavernoside A

✍ Scribed by Kenshu Fujiwara; Akio Murai


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Total Synthesis and
✍ K. FUJIWARA; A. MURAI; M. YOTSU-YAMASHITA; T. YASUMOTO πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 38 KB πŸ‘ 1 views

Total Synthesis and Absolute Configuration of Polycavernoside A. -The first total synthesis of polycavernoside A (XII), a toxin of red alga species, is presented, involving formation of the cyclic acetal (IV), lactonization of secoic acid (V) and rearrangement of the obtained 12-membered lactone (V

ChemInform Abstract: Total Synthesis of
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: Total Synthesis of
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Total Synthesis of (-)-Epothilone A. -A key step in the synthesis of the title antitumor natural product is the highly stereoselective aldol reaction of the optically active building blocks (I) and (II). Esterification of the product (IV) with the subunit (V) leads to the stereochemically homogeneou