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ChemInform Abstract: Total Synthesis of (-)-Eudistomins with an Oxathiazepine Ring. Part 1. Formation of the Oxathiazepine Ring System.

✍ Scribed by Masako Nakagawa; Jin-Jun Liu; Tohru Hino; Akihiko Tsuruoka; Naoyuki Harada; Makoto Ariga; Yasunori Asada


Publisher
John Wiley and Sons
Year
2001
Weight
35 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract 3‐(Methoxymethoxymethyl)‐2‐thiophenesulfonamides and 3‐hydroxymethyl‐__N__‐methoxymethyl‐2‐thiophenesulfonamides have been shown to undergo cyclization when treated under anhydrous acidic conditions to provide the novel 2,3‐dihydro‐5__H__‐thieno[2,3‐__e__]‐4,1,2‐oxathiazepine ring syste