✦ LIBER ✦

ChemInform Abstract: The Use of Zinc Enolates in the Synthesis of a Key Intermediate for the Preparation of Trinem Antibiotics.

✍ Scribed by G. KENNEDY; T. ROSSI; B. TAMBURINI

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199702204

No coin nor oath required. For personal study only.

✦ Synopsis

The Use of Zinc Enolates in the Synthesis of a Key Intermediate for the Preparation of Trinem Antibiotics.

-The reaction of the azetidinone (I) with zinc enolates derived from a chiral methoxycyclohexanone provides the trinem antibiotic key intermediate (III) with good diastereoselectivity. -(KENNEDY, G.;

📜 SIMILAR VOLUMES

ChemInform Abstract: Enantioselective In

ChemInform Abstract: Enantioselective Intramolecular C—H Insertion Route to a Key Intermediate for the Synthesis of Trinem Antibiotics.

✍ Masahiro Anada; Shun-ichi Hashimoto 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Enantioselective Intramolecular C-H Insertion Route to a Key Intermediate for the Synthesis of Trinem Antibiotics. -The new route to the chiral azetidin-2-one title compound (III) is based on the Rh-catalyzed decomposition of the diazoester (I) and following intramolecular carbene C-H insertion. Th

ChemInform Abstract: The Stereoselective

ChemInform Abstract: The Stereoselective Synthesis of 4-Formyltrinem, a Key Intermediate for Novel Trinems.

✍ C. GHIRON; T. ROSSI; R. J. THOMAS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

The Stereoselective Synthesis of 4-Formyltrinem, a Key Intermediate for Novel Trinems. -Title compound (VIII) is a key intermediate for the preparation of a wide range of trinem derivatives. This is demonstrated by performing some Wittig reactions.

ChemInform Abstract: Diastereoselective

ChemInform Abstract: Diastereoselective Synthesis of a Key Intermediate for the Preparation of Tricyclic β-Lactam Antibiotics.

✍ Takaji Matsumoto; Toshiyuki Murayama; Shigeru Mitsuhashi; Takashi Miura 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 2 views

ChemInform Abstract: In situ Activated Z

ChemInform Abstract: In situ Activated Zinc—Copper Couple for the Preparation of a Key Intermediate in the Synthesis of Dideoxyinosine (DDI).

✍ J. L. DILLON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

In situ Activated Zinc-Copper Couple for the Preparation of a Key Intermediate in the Synthesis of Dideoxyinosine (DDI). -Compound (III) is prepared as a key intermediate for the synthesis of the AIDs drug dideoxyinosine. The reaction can be used for the large-scale synthesis of (III). -(DILLON,

ChemInform Abstract: A Practical Synthes

ChemInform Abstract: A Practical Synthesis of a Key Intermediate for the Production of β-Lactam Antibiotics.

✍ G. CAINELLI; P. GALLETTI; D. GIACOMINI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

ChemInform Abstract: Preparation of a Ke

ChemInform Abstract: Preparation of a Key Tricyclic Intermediate for the Synthesis of Pyrroloiminoquinone Natural Products.

✍ G. A. KRAUS; N. SELVAKUMAR 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views