𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Enantioselective Intramolecular C—H Insertion Route to a Key Intermediate for the Synthesis of Trinem Antibiotics.

✍ Scribed by Masahiro Anada; Shun-ichi Hashimoto

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Enantioselective Intramolecular C-H Insertion Route to a Key Intermediate for the Synthesis of Trinem Antibiotics.

-The new route to the chiral azetidin-2-one title compound (III) is based on the Rh-catalyzed decomposition of the diazoester (I) and following intramolecular carbene C-H insertion. The enantioselectivity of this azetidinone formation can be completely reversed by appropriate choice of the Rh-catalyst. -(ANADA, MASAHIRO;

📜 SIMILAR VOLUMES

ChemInform Abstract: The Use of Zinc Eno
ChemInform Abstract: The Use of Zinc Enolates in the Synthesis of a Key Intermediate for the Preparation of Trinem Antibiotics.
✍ G. KENNEDY; T. ROSSI; B. TAMBURINI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 2 views

The Use of Zinc Enolates in the Synthesis of a Key Intermediate for the Preparation of Trinem Antibiotics. -The reaction of the azetidinone (I) with zinc enolates derived from a chiral methoxycyclohexanone provides the trinem antibiotic key intermediate (III) with good diastereoselectivity. -(KENNE

ChemInform Abstract: The Stereoselective
ChemInform Abstract: The Stereoselective Synthesis of 4-Formyltrinem, a Key Intermediate for Novel Trinems.
✍ C. GHIRON; T. ROSSI; R. J. THOMAS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

The Stereoselective Synthesis of 4-Formyltrinem, a Key Intermediate for Novel Trinems. -Title compound (VIII) is a key intermediate for the preparation of a wide range of trinem derivatives. This is demonstrated by performing some Wittig reactions.

ChemInform Abstract: Synthesis and NMR S
ChemInform Abstract: Synthesis and NMR Studies of Key Intermediates to a New Class of β -Lactam: The Trinems.
✍ C. MARCHIORO; G. PENTASSUGLIA; A. PERBONI; D. DONATI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

Synthesis and NMR Studies of Key Intermediates to a New Class of β -Lactam: The Trinems. -All 4 isomeric epoxides (X), (XI), (XIV), and (XV), which are key intermediates for trinems, a new family of antibiotics, are synthesized starting from the azetidinone (I). -(MARCHIORO, C.;

ChemInform Abstract: Stereocontrolled Sy
ChemInform Abstract: Stereocontrolled Synthesis of the Key Intermediate for the Enantioselective Synthesis of Clerodane Natural Products
✍ M. KATO; H. KOSUGI; A. KODAIRA; H. HAGIWARA; B. VOGLER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v